PHYSIOLOGIC MEDIUM RENDERS HUMAN IPSC-DERIVED MACROPHAGES PERMISSIVE FOR M. TUBERCULOSIS BY REWIRING ORGANELLE FUNCTION AND METABOLISM

Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

ABSTRACT In vitro studies are crucial for our understanding of the human macrophage immune functions.However, traditional in vitro culture media poorly reflect custom congratulations banner the metabolic composition of blood, potentially affecting the outcomes of these studies.Here, we analyzed the impact of a physiological medium on human induced

read more

Unexpected cranial sexual dimorphism in the tragulid Dorcatherium naui based on material from the middle to late Miocene localities of Eppelsheim and Hammerschmiede (Germany).

Tragulids, chevrotains or mouse deer, were common faunal elements during the Miocene.During that time, Dorcatherium was the most abundant genus, with D.naui being the first described species.Besides their abundance, until recently only very limited cranial material was available for investigation.Here we present a redescription of the first complet

read more